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Links about TIC Genetics Study

Publications

  • Analysis of shared heritability in common disorders of the brain. Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126/science.aap8757. Press release. (Click here to view)
  • Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. Eur Arch Psychiatry Clin Neurosci. 268: 301–316, 2018. PMCID: PMC5708161. (Click here to view)
  • The PNKD gene is associated with Tourette Disorder or Tic disorder in a multiplex family. Mol Psychiatry doi: 10.1038/mp.2017.179. [Epub ahead of print], 2017. PMCID: PMC5847395. Press release. (Click here to view)
  • Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach. Eur Arch Psychiatry Clin Neurosci. Published online: DOI 10.1007/s00406-017-0808-8, 2017. PMCID: PMC Journal – In Process. (Click here to view)
  • De novo coding mutations are strongly associated with Tourette Disorder. Neuron. 94:486–499, 2017. PMCID: PMC Journal – In Process.  Press release. (Click here to view)
  • Targeted re-sequencing approach of Gilles de la Tourette Syndrome candidate genes implicates rare potentially functional variants in Tourette Syndrome etiology. Front. Neurosci. 10:428, doi: 10.3389/fnins.2016.00428, 2016. PMCID: PMC5026935. (Click here to view)
  • Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder. Journal of Psychiatric Research 82:126–135, 2016. PMCID: PMC5026935. (Click here to view)
  • The Genetic Etiology of Tourette Syndrome: Large-Scale Collaborative Efforts on the Precipice of Discovery. Front Neurosci. 2016 Aug 3;10:351. doi: 10.3389/fnins.2016.00351. (Click here to view)
  • Functional evaluations of genes disrupted in patients with Tourette’s Disorder. Front. Psychiatry 7:11, doi: 10.3389/fpsyt.2016.00011, 2016. PMCID: PMC4746269. (Click here to view)
  • GDNF gene is associated with Tourette syndrome in a family study. Mov Disord 30:1115–1120, 2015. PMCID: PMC5036394. (Click here to view)
  • Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis. Eur J Hum Genet. 23:1519–1522, 2015. PMCID: PMC4613465. (Click here to view)
  • The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods. Eur Child Adolesc Psychiatry 24:141–151, 2015. PMCID: PMC4209328. (Click here to view)
  • Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette’s Syndrome and OCD. Am J Psychiatry 172:82–93, 2015. PMCID: PMC4282594. (Click here to view)
  • The Inheritance of Tourette Disorder: A review. J Obsessive Compuls Relat Disord. 2014 Oct 1;3(4):380-385. (Click here to view)
  • Copy number variation in obsessive-compulsive disorder and Tourette syndrome: a cross-disorder study. J Am Acad Child Adolesc Psychiatry 53:910–919, 2014. PMCID: PMC4218748. (Click here to view)
  • Genetic susceptibility and neurotransmitters in Tourette syndrome. Int Rev Neurobiol 112:155–77, 2013. PMCID: PMC4471172. (Click here to view)
  • Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecturePLoS Genet 9(10): e1003864. doi:10.1371/journal.pgen.1003864, 2013. PMCID: PMC3812053. (Click here to view)
  • Common and rare gain-of-function alleles of the serotonin transporter gene, SLC6A4, associated with Tourette disorder. Mov Disord 28:1263–70, 2013. PMCID: PMC3766488. (Click here to view)
  • Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes. Eur J Hum Genet 21:850–854, 2013. PMCID: PMC3722668. (Click here to view)
  • Genome-wide association study of Tourette’s syndrome. Mol Psychiatry 18:721–728, 2013. PMCID: PMC3605224.
  • Rare copy number variants in Tourette syndrome disrupt genes in histaminergic pathways and overlap with autism. Biol Psychiatry 71:392–402, 2012. PMCID: PMC3282144. (Click here to view)
  • L-histidine decarboxylase and Tourette’s syndrome. N Engl J Med 362:1901–8, 2010. PMCID: PMC2894694. (Click here to view)
  • New Jersey Center for Tourette Syndrome sharing repository: methods and sample description. BMC Medical Genomics 1:58, 2008. URL: http://www.biomedcentral.com/1755-8794/1/58, PMCID: PMC2605751 (Click here to view)